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These findings further support that the carrier does not induce manganese accumulation or related toxicity

Evidently, there is only partial conservation in the PfTrx-2 active site residues and PfTrx-2 structure reveals several unique features when compared to its human counterpart (HuTrx-2)

SOD, catalase, and glutathione peroxidase are the primary antioxidant enzymes that inactivate the ROS into intermediates [13]

Baseline and periodic blood pressure measurements, particularly in patients with cardiovascular disease or those taking cardiovascular medications, would identify any clinically significant hemodynamic effects